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Chapter 17: From Gene to Protein This is going to be a very long journey, but it is crucial to your understanding of biology. Work on this chapter a single concept at a time, and expect to spend at least 6 hours to truly master the material. To give you an idea of the depth and time required, we have spent over 5 hours writing this Reading Guide!
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Historical experiments: Garrod's studies of alkaptonuria, Beadle and Tatum's work with Neurospora mutants.
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The actual cause of this mutation is a gene disorder, where the sixth codon of the protein glutamaric acid is changed with valine. This small change in the genetic code can cause severe defects in the effected such as blood clots, severe disorders and even death.
I note that the 'Explain to a Layman' tag has been added, so I have tried to craft my answer accordingly. Rather lengthy, I know, but I have tried to give a fairly complete summary of a complex aspect of biology. In short, the 'one gene-one polype.
Gene structure. Genes are DNA sequences that code for a protein. It is an unusual feature of most genes that the sequence of nucleotides that code for a protein is regularly interrupted by non.